Due to the specific character of Czech beer, that is, the water, malt, hops and yeast used in the brewing, Czech brewers want recognition of the uniqueness of their beer. Ĭzech beer is unique because it is brewed using specific technology and at a particular latitude. The beer industry of the Czech Republic (Bohemia) has a long history since the first Czech brewery was founded in 993 at Břevnov Monastery in Prague, and it was only in October 2008, when the EU allowed the Czech Republic to use the “Ceské pivo/Czech Beer” trademark. The brewing industry is a global business in traditional European brewing regions with local varieties of beer still maintained mostly in central Europe. It acts as a nutritional supplement with many bioactive molecules, as it contains readily available starches and sugars, various minerals and valuable B vitamins. īeer is not only considered as a beverage, but it provides a valuable added value to the diet. The different contributions like the use of hops, yeast, the different fermentation methods and the high technology development in the last century have contributed to the growth, improvement and variety of brewing as is currently known. Approximately 6000 years ago, ancient texts revealed the first beer production by the Sumerians: “the sweetest grain, if baked, left out, moistened, forgotten, and then eaten, would produce an uplifting, cheerful feeling”. Conclusions: The promising effects shown by freeze-dried Czech beers due to their safety, protection against a toxin, chemopreventive potential and the induction of DNA damage in tumour cells, allow the proposition of Czech beer as a beverage with nutraceutic potential.īeer is one of the oldest known beverages. Moreover, all the substances were able to inhibit the tumour cell growth and to induce DNA damage in the HL-60 cells at different levels (proapoptotic, single/double strands breaks and methylation status). Results: The safe effects for all the analysed substances and general protective effects against H 2O 2 were shown both at the individual and genomic level in the Drosophila animal model, with some exceptions. Methods: In vivo assays to evaluate the safety and protective effects in the Drosophila melanogaster eukaryotic system, and the in vitro evaluations of chemopreventive and DNA damage activity using the HL-60 tumour human cell line were carried out. The purpose of this work is the evaluation of toxicological effects of a variety of freeze-dried Czech beers, their raw materials (malts, hops and yeast) and processed-beer (wort, hopped wort and young beer). Background: Czech beers are unique because they are brewed using specific technology at a particular latitude and for being entirely produced in the area of the Czech Republic.

Pilsner urquell draft